CAFFEINE, POSTOPERATIVE DELIRIUM AND CHANGE IN OUTCOMES AFTER SURGERY (CAPACHINOS)-2: PROTOCOL FOR A RANDOMISED CONTROLLED TRIAL

Introduction Delirium is a major public health issue for surgical patients and their families because it is associated with increased mortality, cognitive and functional decline, prolonged hospital admission and increased healthcare expenditures.Based on preliminary data, this trial tests the hypothesis that intravenous caffeine, given postoperativ

Abstract Inverse Protein Folding (IPF) is an important task of protein design, which aims to design sequences compatible with a given backbone structure.Despite the prosperous development of algorithms for kt196 torque converter this task, existing methods tend to rely on noisy predicted residues located in the local neighborhood when generating se